Associate Professor of Laboratory Medicine and Pathology, and Director of Advanced Research and Diagnostic Laboratory
University of Minnesota
"Improving Diagnosis of Acute Myocardial Infarction with High-Sensitivity Cardiac Troponin Assays: Insights from a Clinical Chemist"
Laboratory medicine is essential for patient care and results from laboratory tests are routinely utilized to make medical decisions, including diagnosis, prognosis and guiding therapy. One of the major areas of interest in clinical chemistry focuses on new biomarkers to improve cardiovascular morbidity and mortality. Cardiac troponin is a biomarker of myocardial necrosis used to diagnose acute myocardial infarction in the Emergency Room and the field is rapidly evolving with introduction of high-sensitivity cardiac troponin assays into clinical practice. The utility of high-sensitivity troponin assays extends beyond the Emergency Room, with research evolving in the areas of pediatrics, diabetes, heart failure, and cardio-oncology. This presentation will focus on research related to cardiovascular biomarkers and also highlight the role a clinical chemist plays in directly helping physicians make decisions on a daily basis. Clinical chemists provide guidelines and recommendations for use of laboratory testing but also play a role in the discovery, development, and implementation of new laboratory tests.